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Article

Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.

Atherosclerosis - 1 Jun 2001

Sentí M, Tomás M, Vila J, Marrugat J, Elosua R, Sala J, Masiá R

Abstract excerpt

Paraoxonase1 (PON1) seems to exert a major antioxidant effect by removing lipid-peroxidation products. A common polymorphism of the PON1 gene, the PON1-192 genetic polymorphism, modulates PON1 activity and has been related in some studies to coronary heart disease. Oxidized LDL is believed to play a crucial role in the pathogenesis of atherosclerosis and there are studies providing support for the oxidative...

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Source

Identifiers

PMID: 11395042
DOI: 10.1016/s0021-9150(00)00680-8

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.PMID 11395042Read ↗

Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene.Semantic proximity Read ↗

Paraoxonase1-192 polymorphism modulates the nonfatal myocardial infarction risk associated with decreased HDLs.Semantic proximity Read ↗

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Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women.Semantic proximity Read ↗

The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.Semantic proximity Read ↗

PON1 is a longevity gene: results of a meta-analysis.Semantic proximity Read ↗

Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.Semantic proximity Read ↗

Paraoxonase 1 gene polymorphisms and enzyme activities in coronary artery disease and its relationship to serum lipids and glycemia.Semantic proximity Read ↗

Quantitative Assessment of the Influence of Paraoxonase 1 Activity and Coronary Heart Disease RiskSemantic proximity Read ↗

Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk.Semantic proximity Read ↗

The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.Semantic proximity Read ↗

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