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Article

Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2000

Sen-Banerjee S, Siles X, Campos H

Abstract excerpt

Paraoxonase, a high density lipoprotein-associated human serum enzyme, plays a role in atherosclerosis by protecting against lipid peroxidation. Its activity is modulated by 2 common amino acid polymorphisms at positions 192 (Gln-->Arg) and 55 (Met-->Leu) in the paraoxonase gene (P:ON1). We studied the association of P:ON1 polymorphisms and myocardial infarction (MI) in a population-based study consisting of 492...

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Source

Identifiers

PMID: 10978258
DOI: 10.1161/01.atv.20.9.2120

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.PMID 10978258Read ↗

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Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.Semantic proximity Read ↗

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