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Article

The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.

Angiology - 1 Feb 2010

Gluba Anna, Pietrucha Tadeusz, Banach Maciej, Piotrowski Grzegorz, Rysz Jacek

Abstract excerpt

Paraoxonases (PONs) may exert anti-atherogenic action by reducing lipid peroxidation. We evaluated the influence of 2 polymorphisms within PON1 (192 Gln/ Arg) and PON2 (311 Ser/Cys) genes in 407 young Poles: 273 patients who experienced a first myocardial infarction (MI) under the age of 45 (study group) and 134 healthy volunteers (control group) with a HEART Score < or =2 (low risk). Paraoxonase 1 polymorphism...

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Source

Identifiers

PMID: 19939821
DOI: 10.1177/0003319709351258

Genes

PON1
CAD
PON2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.PMID 19939821Read ↗

Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.Semantic proximity Read ↗

Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene.Semantic proximity Read ↗

The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients.Semantic proximity Read ↗

DNA polymorphisms in two paraoxonase genes (PON1 and PON2) are associated with the risk of coronary heart disease.Semantic proximity Read ↗

Paraoxonase 1 L55M, Q192R and paraoxonase 2 S311C alleles in atherothrombosis.Semantic proximity Read ↗

Tobacco smoking modifies association between Gln-Arg192 polymorphism of human paraoxonase gene and risk of myocardial infarction.Semantic proximity Read ↗

Paraoxonase1-192 polymorphism modulates the nonfatal myocardial infarction risk associated with decreased HDLs.Semantic proximity Read ↗

The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.Semantic proximity Read ↗

Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.Semantic proximity Read ↗

The risk of coronary artery disease in population of Taiwan is associated with Cys-Ser 311 polymorphism of human paraoxonase (PON)-2 gene.Semantic proximity Read ↗

Evaluation of the paraoxonases as candidate genes for stroke: Gln192Arg polymorphism in the paraoxonase 1 gene is associated with increased risk of stroke.Semantic proximity Read ↗

Association of cys 311 ser polymorphism of paraoxonase-2 gene with the risk of coronary artery disease.Semantic proximity Read ↗

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