Article
The tau A0 allele in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 May 2001
Golbe L I, Lazzarini A M, Spychala J R, Johnson W G, Stenroos E S, Mark M H, Sage J I
Abstract excerpt
Parkinson's disease (PD) is primarily an alpha-synucleinopathy, rather than a tauopathy, but there is evidence for an indirect association of tau with the pathogenetic process in PD. We therefore assessed the frequency in PD of the tau A0 allele, a dinucleotide repeat marker that has been associated with a sporadic tauopathy, progressive supranuclear palsy (PSP). We found the A0 allele to comprise 79.2% of 758...
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