Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype.

doi:10.1002/mds.26022

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Article

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype.

Movement disorders : official journal of the Movement Disorder Society - 1 May 2015

Swanson Christine R, Li Katherine, Unger Travis L, Gallagher Michael D, Van Deerlin Vivianna M, Agarwal Pinky, Leverenz James, Roberts John, Samii Ali, Gross Rachel Goldmann, Hurtig Howard, Rick Jacqueline, Weintraub Daniel, Trojanowski John Q, Zabetian Cyrus, Chen-Plotkin Alice S

Abstract excerpt

The discovery of novel plasma-based biomarkers could lead to new approaches in the treatment of Parkinson's disease (PD). Here, we explore the role of plasma apolipoprotein A1 (ApoA1) as a risk marker for PD and evaluate the influence of APOA1 promoter variation on plasma ApoA1 levels. Plasma ApoA1 and the single-nucleotide polymorphism, rs670, were assayed in a discovery cohort (cohort 1) of 301 PD patients, 80...

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PMID: 25227208
DOI: 10.1002/mds.26022
PMCID: PMC4362847

Genes

APOA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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