Article
Direct genetic evidence for involvement of tau in progressive supranuclear palsy. European Study Group on Atypical Parkinsonism Consortium.
Neurology - 1 Oct 1998
Bennett P, Bonifati V, Bonuccelli U, Colosimo C, De Mari M, Fabbrini G, Marconi R, Meco G, Nicholl D J, Stocchi F, Vanacore N, Vieregge P, Williams A C
Abstract excerpt
OBJECTIVE: To confirm whether a dinucleotide repeat sequence in an intron of the microtubule-associated protein tau is associated with progressive supranuclear palsy (PSP) in an independent study population and to establish an improved methodology for allelotyping. BACKGROUND: It has recently bee...
Topics
- Aged
- Aged, 80 and over
- Alleles
- DNA Mutational Analysis
- Diagnosis, Differential
- Dinucleotide Repeats
- Female
- Fluorescent Dyes
- Genetic Markers
- Genotype
- Humans
- Introns
- Male
- Middle Aged