Article
Direct genetic evidence for involvement of tau in progressive supranuclear palsy. European Study Group on Atypical Parkinsonism Consortium.
Neurology - 1 Oct 1998
Bennett P, Bonifati V, Bonuccelli U, Colosimo C, De Mari M, Fabbrini G, Marconi R, Meco G, Nicholl D J, Stocchi F, Vanacore N, Vieregge P, Williams A C
Abstract excerpt
OBJECTIVE: To confirm whether a dinucleotide repeat sequence in an intron of the microtubule-associated protein tau is associated with progressive supranuclear palsy (PSP) in an independent study population and to establish an improved methodology for allelotyping. BACKGROUND: It has recently been reported that a genetic variant of tau, known as the A0 allele, was represented excessively in PSP patients when...
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