Article
Polymorphisms in the tau gene in sporadic frontotemporal dementia and other neurodegenerative disorders.
European journal of neurology - 1 Sept 2002
Panegyres P K, Zafiris-Toufexis K
Abstract excerpt
The tau gene on chromosome 17 is fundamental in the pathogenesis of a number of neurodegenerative disorders. Mutations in tau are found in familial frontotemporal dementia (FTD) and the A0/A0 genotype associated with progressive supranuclear palsy (PSP). This study investigates the hypothesis that polymorphisms in the tau gene are associated with sporadic FTD. Western Australian populations of patients with...
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