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Article

Expression of Moloney murine leukemia virus RNase H rescues the growth defect of an Escherichia coli mutant.

Journal of virology - 1 Jul 2001

Campbell A G

Abstract excerpt

A 157-amino-acid fragment of Moloney murine leukemia virus reverse transcriptase encoding RNase H is shown to rescue the growth-defective phenotype of an Escherichia coli mutant. In vitro assays of the recombinant wild-type protein purified from the conditionally defective mutant confirm that it is catalytically active. Mutagenesis of one of the presumptive RNase H-catalytic residues results in production of a...

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Identifiers

PMID: 11390625
DOI: 10.1128/JVI.75.13.6212-6217.2001
PMCID: PMC114339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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