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Article

Correlation of activity with phenotypes of Escherichia coli partial function mutants of rnh, the gene encoding RNase H.

Molecular & general genetics : MGG - 1 Jul 1991

Itaya M, Crouch R J

Abstract excerpt

The rnh gene of Escherichia coli encodes RNase H. rnh mutants display at least two phenotypes: (1) they require functional RecBCD enzyme for growth; thus rnh-339::cat recB270 (Ts) and rnh-339::cat recC271 (Ts) strains are temperature sensitive for growth; (2) rnh mutants permit replication that is independent of the chromosomal origin, presumably by failing to remove RNA-DNA hybrids from which extra-original...

Topics

Alleles
Endoribonucleases
Escherichia coli
Genes, Bacterial
Mutation
Nucleic Acid Hybridization
Phenotype
Plasmids
Ribonuclease H
Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1650909
DOI: 10.1007/BF00273934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1650909-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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