Article
Correlation of activity with phenotypes of Escherichia coli partial function mutants of rnh, the gene encoding RNase H.
Molecular & general genetics : MGG - 1 Jul 1991
Itaya M, Crouch R J
Abstract excerpt
The rnh gene of Escherichia coli encodes RNase H. rnh mutants display at least two phenotypes: (1) they require functional RecBCD enzyme for growth; thus rnh-339::cat recB270 (Ts) and rnh-339::cat recC271 (Ts) strains are temperature sensitive for growth; (2) rnh mutants permit replication that is independent of the chromosomal origin, presumably by failing to remove RNA-DNA hybrids from which extra-original...
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