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Ribonuclease H: from discovery to 3D structure.

The New biologist - 1 Sept 1990

Crouch R J

Abstract excerpt

Ribonucleases H (RNases H) from Escherichia coli and retroviruses share common features at the primary amino acid sequence and activity levels. RNase H is involved in selection of the origins of replication in E. coli and in DNA synthesis of the positive strand of retroviruses. Crystallographic studies of E. coli RNase H indicate that several amino acids, conserved in both cellular and retroviral RNases H, form...

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PMID: 2177653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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