Article
Apoptotic, necrotic, or fused tumor cells: an equivalent source of antigen for dendritic cell loading.
Apoptosis : an international journal on programmed cell death - 1 Sept 2006
Larmonier Nicolas, Mérino Delphine, Nicolas Alexandra, Cathelin Dominique, Besson Angélique, Bateman Andrew, Solary Eric, Martin François, Katsanis Emmanuel, Bonnotte Bernard
Abstract excerpt
The identification of the most efficient strategy for tumor antigen loading of dendritic cells (DCs) remains a challenge in cancer immunotherapy protocols. Autologous dead tumor cells have been demonstrated to constitute an acceptable source of multiple tumor-associated antigens (TAA) to pulse DC...
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