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Article

The receptor for the type I insulin-like growth factor and its ligands regulate multiple cellular functions that impact on metastasis.

Surgical oncology clinics of North America - 1 Apr 2001

Samani A A, Brodt P

Abstract excerpt

The receptor for the type I insulin-like growth factor (IGF-IR) has been identified as a regulator of cellular transformation and the acquisition of the tumorigenic phenotype. This article reviews recent evidence including the authors' own, which implicates this receptor and its ligands IGF-I and IGF-II in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11382588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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