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Article

The Effects of Insulin-Like Growth Factors on Tumorigenesis and Neoplastic Growth

2000-06-01

Abstract excerpt

Several decades of basic and clinical research have demonstrated that there is an association between the insulin-like growth factors (IGFs) and neoplasia. We begin with a brief discussion of the function and regulation of expression of the IGFs, their receptors and the IGF-binding proteins (IGFBPs). A number of investigational interventional strategies targeting the GH or IGFs are then reviewed. Finally, we have...

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Identifiers and source

Literature Corpus work
08841350-a224-55c5-b0ad-a043e4f85ef7
DOI
10.1210/er.21.3.215
Open publication

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