Article
The insulin-like growth factor I receptor: a key to tumor growth?
Cancer research - 15 Jan 1995
Baserga R
Abstract excerpt
The insulin-like growth factor I receptor (IGF-IR) belongs to the family of transmembrane tyrosine kinase receptors, like the receptors for platelet-derived growth factor, the epidermal growth factor, insulin, and others. Genetic evidence has shown that the IGF-IR is required for optimal growth i...
Topics
- Animals
- Apoptosis
- Cell Division
- Cell Transformation, Neoplastic
- Cell Transformation, Viral
- Glioblastoma
- Humans
- Melanoma
- Mice
- Mice, Nude
- Phenotype
- Rats
- Receptor, IGF Type 1
