Article
Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map.
Nature genetics - 1 Jun 2001
Wicks S R, Yeh R T, Gish W R, Waterston R H, Plasterk R H
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are valuable genetic markers of human disease. They also comprise the highest potential density marker set available for mapping experimentally derived mutations in model organisms such as Caenorhabditis elegans. To facilitate the positional cloning of mutations we have identified polymorphisms in CB4856, an isolate from a Hawaiian island that shows a uniformly high density...
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