Article
A universal method for automated gene mapping.
Genome biology - 1 Jan 2005
Zipperlen Peder, Nairz Knud, Rimann Ivo, Basler Konrad, Hafen Ernst, Hengartner Michael, Hajnal Alex
Abstract excerpt
Small insertions or deletions (InDels) constitute a ubiquituous class of sequence polymorphisms found in eukaryotic genomes. Here, we present an automated high-throughput genotyping method that relies on the detection of fragment-length polymorphisms (FLPs) caused by InDels. The protocol utilizes standard sequencers and genotyping software. We have established genome-wide FLP maps for both Caenorhabditis elegans...
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