Article
FLP-Mapping: a universal, cost-effective, and automatable method for gene mapping.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Nairz Knud, Zipperlen Peder, Schneider Manuel
Abstract excerpt
Genetic mapping with DNA sequence polymorphisms allows for map-based positional cloning of mutations at any required resolution. Numerous methods have been worked out to assay single nucleotide polymorphisms (SNPs), the most common type of molecular polymorphisms. However, SNP genotyping requires customized and often costly secondary assays on primary PCR products. Small insertions and deletions (InDels) are a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.