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Article

Resolution of cis-trans ambiguities between HLA-DRB1 alleles using single-strand conformation polymorphisms and sequencing.

Tissue antigens - 1 Apr 2001

Paul P, Thomas D, Kawczak P, Good D, Cook D J, Ball E J

Abstract excerpt

DNA-based typing of HLA alleles occasionally results in the inability to assign a specific allele because of ambiguity in associating two or more polymorphisms to the same or to alternate homologs (cis/trans ambiguity). Since most individuals are heterozygous at a given HLA locus, the highest lev...

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Share to Histocompatibility Testing
Share to HLA-DR Antigens
Share to HLA-DRB1 Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nucleic Acid Conformation

Share to Polymorphism, Single-Stranded Conformational

Share to Reproducibility of Results

Share to Sequence Homology, Amino Acid

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 11380938
DOI: 10.1034/j.1399-0039.2001.057004300.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11380938-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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