Article
Reanalysis of sequence-based HLA-A, -B and -Cw typings: how ambiguous is today's SBT typing tomorrow.
Tissue antigens - 1 Nov 2007
Voorter C E M, Mulkers E, Liebelt P, Sleyster E, van den Berg-Loonen E M
Abstract excerpt
The permanently increasing number of human leukocyte antigen (HLA)-alleles and the growing list of ambiguities require continuous updating of high-resolution HLA typing results. Two different kinds of ambiguities exist: the first, when two or more allele combinations have identical heterozygous sequences, and the second, when differences are located outside the analyzed region. The number of HLA-A, B and C...
Topics
- Alleles
- Databases, Genetic
- Female
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- Heterozygote
- Histocompatibility Testing
- Humans
- Male
- Retrospective Studies
