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Article

Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions.

Mutation research - 2 Jun 2001

Meira L B, Reis A M, Cheo D L, Nahari D, Burns D K, Friedberg E C

Abstract excerpt

Mouse models that mimic the human skin cancer-prone disease xeroderma pigmentosum (XP) provide an useful experimental system with which to study the relationship between the DNA repair process of nucleotide excision repair (NER) and ultraviolet- (UV) induced skin carcinogenesis. We have generated Xpc mutant mice and documented their deficiency in the process of NER of UV-induced DNA damage. Xpc mutant mice are...

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Source

Identifiers

PMID: 11376686
DOI: 10.1016/s0027-5107(01)00097-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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