Article
The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal.
JAMA - 7 Apr 1993
Gelernter J, Goldman D, Risch N
Abstract excerpt
OBJECTIVE: An allelic association between the TaqI "A" system A1 allele at the D2 dopamine receptor locus (DRD2) and either alcoholism or severe alcoholism has been proposed. Our purpose was to evaluate whether, based on all of the accumulated evidence, this association could be considered to be proven. DATA SOURCES: We considered data from all published reports of DRD2 allele frequency in alcoholics, controls,...
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