Article
The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders.
JAMA - 2 Oct 1991
Comings D E, Comings B G, Muhleman D, Dietz G, Shahbahrami B, Tast D, Knell E, Kocsis P, Baumgarten R, Kovacs B W
Abstract excerpt
OBJECTIVE: --The A1 allele of the Taq I polymorphism of the dopamine D2 receptor (DRD2) gene has been earlier reported to occur in 69% of alcoholics, compared with 20% of controls. Other research has reported no significant difference in the prevalence of the A1 allele in alcoholics vs controls a...
Topics
- Alcoholism
- Alleles
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Brain Diseases
- Chromosome Aberrations
- Chromosome Disorders
- DNA
- DNA-Directed DNA Polymerase
- Genotype
- Humans
- Mental Disorders
- Parkinson Disease
- Receptors, Dopamine
- Receptors, Dopamine D2