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Article

Molecular Cloning of the CA125 Ovarian Cancer Antigen

1 Jul 2001

Abstract excerpt

CA125 is an ovarian cancer antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian cancer; however, detailed information on its biochemical and molecular nature is lacking. We now report the isolation of a long, but partial, cDNA that corresponds to the CA125 antigen. A rabbit polyclonal antibody produced to purified CA125 antigen was used to screen a lambdaZAP cDNA...

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Identifiers

PMID: 11369781
DOI: 10.1074/jbc.m103554200

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