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Article

Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer.

Biological research for nursing - 1 Apr 2005

McLemore Monica R, Aouizerat Bradley

Abstract excerpt

More than 24,000 women in the United States are diagnosed with ovarian cancer every year, and half of these women die from their disease. Stage 1 ovarian cancer is curable in 95% of cases; however, due to inadequate screening tools and lack of symptoms in early disease, ovarian cancer is generally at Stage 3 or 4 when finally diagnosed. CA125 is a tumor antigen used to monitor the progression and regression of...

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Identifiers

PMID: 15788735
DOI: 10.1177/1099800404274445

Genes

MUC16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer.PMID 15788735Read ↗

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Polymorphisms of MUC16 (CA125) and MUC1 (CA15.3) in relation to ovarian cancer risk and survival.Semantic proximity Read ↗

Ovarian cancer antigen CA125 is encoded by the <i>MUC16</i> mucin geneSemantic proximity Read ↗

Polymorphisms in the MUC16 gene: potential implication in epithelial ovarian cancer.Semantic proximity Read ↗

CA125/MUC16 is dispensable for mouse development and reproduction.Semantic proximity Read ↗

A Revised Molecular Model of Ovarian Cancer Biomarker CA125 (MUC16) Enabled by Long-read SequencingSemantic proximity Read ↗

Molecular Cloning of the CA125 Ovarian Cancer AntigenSemantic proximity Read ↗

MUC16 mutations improve patients’ prognosis by enhancing the infiltration and antitumor immunity of cytotoxic T lymphocytes in the endometrial cancer microenvironmentSemantic proximity Read ↗

Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancerSemantic proximity Read ↗

MUC16 impacts tumor proliferation and migration through cytoplasmic translocation of P120-catenin in epithelial ovarian cancer cells: an original researchSemantic proximity Read ↗

Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor markerSemantic proximity Read ↗

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