Article
Transcriptional regulation of the leptin gene promoter in rat GH3 pituitary and C6 glioma cells.
Molecular and cellular endocrinology - 15 May 2001
Li A W, Morash B, Hollenberg A N, Ur E, Wilkinson M, Murphy P R
Abstract excerpt
Leptin was originally believed to be an exclusively adipocyte-derived hormone regulating appetite and energy balance. It has recently become apparent that leptin is actively expressed in a number of other tissues including the CNS and pituitary, as well as brain- and pituitary-derived cell lines. However, the factors controlling leptin expression in cells of neuroectodermal origin are unknown. The mouse leptin...
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