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Article

Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression

14 Feb 2015

Abstract excerpt

OBJECTIVE: Leptin gene expression is highly correlated with cellular lipid content in adipocytes but the transcriptional mechanisms controlling leptin expression in vivo are poorly understood. In this report, we set out to identify cis- and trans-regulatory elements controlling leptin expression. METHODS: Leptin-BAC luciferase transgenic mice combining with other computational and molecular techniques were used...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 25973387
DOI: 10.1016/j.molmet.2015.02.002

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