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Article

The leptin receptor promoter controls expression of a second distinct protein

15 Jul 1997

Abstract excerpt

The leptin receptor (OB-R) is a single membrane- spanning protein that mediates the weight-regulatory effects of leptin (OB protein). Several mRNA splice variants have been described which either encode OB-R proteins with cytoplasmic domains of different length or the OB-R and B219/OBR variants, which have different 5'-untranslated regions. Here we report evidence for the synthesis of a human mRNA splice variant...

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PMID: 9207021
DOI: 10.1093/nar/25.14.2752

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