Article

Quantitative expression of genes involved in the leptin receptor-mediated STAT signalling pathway in rodent models of obesity

2001-01-01

Abstract excerpt

In most cases of human obesity serum leptin levels are elevated, suggesting that reduced sensitivity to endogenous leptin may contribute towards the increase in body weight. There are several potential areas that may be involved in reduced leptin sensitivity, including the blood-brain-barrier (BBB) transport system, changes in expression of the functional leptin receptor, OB- Rb, and components of the leptin recep...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02edbf22-4348-5d03-ae47-f39d41f12d53
DOI: 10.5525/gla.thesis.72316

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quantitative expression of genes involved in the leptin receptor-mediated STAT signalling pathway in rodent models of obesityDOI 10.5525/gla.thesis.72316Read

Leptin signaling.Semantic proximity Read

[Leptin Receptor].Semantic proximity Read

Structure, production and signaling of leptin.Semantic proximity Read

Leptin Signaling in the Central Nervous System and the PeripherySemantic proximity Read

Adipose tissue gene expression profiles in ob/ob mice treated with leptinSemantic proximity Read

Leptin: Genes, Concepts and Clinical PerspectiveSemantic proximity Read

Regulation of energy balance by leptinSemantic proximity Read

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset.Semantic proximity Read

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.Semantic proximity Read

Leptin and OB-R: Body weight regulation by a cytokine receptorSemantic proximity Read

Human leptin: an adipocyte hormone with weight-regulatory and endocrine functions.Semantic proximity Read

Leptin participates in the regulation of glucocorticoid and growth hormone axesSemantic proximity Read