Genetic and functional changes in mitochondria associated with aging.

doi:10.1152/physrev.1997.77.2.425

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Article

Genetic and functional changes in mitochondria associated with aging.

Physiological reviews - 1 Apr 1997

Ozawa T

Abstract excerpt

This review is devoted to the molecular genetics and bioenergetics of human mitochondria related to the mechanism of aging. Morphological and functional changes of mitochondria associated with age and age-related disease are overviewed with special reference to the changes in enzymes encoded by m...

Topics

Aging
Animals
DNA, Mitochondrial
Humans
Mitochondria
Models, Biological
Mutation

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