Article
Absence of PPP2R1A mutations in Wilms tumor.
Oncogene - 12 Apr 2001
Ruteshouser E C, Ashworth L K, Huff V
Abstract excerpt
Evidence from genetic linkage analysis indicates that a gene located at 19q13.4, FWT2, is responsible for predisposition to Wilms tumor in many Wilms tumor families. This region has also been implicated in the etiology of sporadic Wilms tumor through loss of heterozygosity analyses. The PPP2R1A gene, encoding the alpha isoform of the heterotrimeric serine/threonine protein phosphatase 2A (PP2A), is located within...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
