Article
HLA-DRB1 gene transcripts in rheumatoid arthritis.
Clinical and experimental immunology - 1 Apr 2001
Kerlan-Candon S, Combe B, Vincent R, Clot J, Pinet V, Eliaou J F
Abstract excerpt
Susceptibility to rheumatoid arthritis (RA) is associated with defined HLA-DRB1 alleles. However the molecular basis of this association is not known. Peculiarities in the expression of disease-linked DRB1 alleles could be involved since in healthy controls HLA-DRB1 gene expression varies according to the alleles in B cells. Peripheral blood B cells of healthy controls and RA patients were examined for their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
