Article
The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis.
Annals of internal medicine - 15 Nov 1992
Weyand C M, Hicok K C, Conn D L, Goronzy J J
Abstract excerpt
OBJECTIVE: To explore the role of HLA-DRB1 genes in determining disease severity in rheumatoid arthritis. DESIGN: Case series of patients with seropositive rheumatoid arthritis. SETTING: The outpatient clinic of the Division of Rheumatology, Mayo Clinic. PATIENTS: One hundred and two patients wit...
Topics
- Aged
- Alleles
- Amino Acid Sequence
- Arthritis, Rheumatoid
- Base Sequence
- Chi-Square Distribution
- Female
- Gene Expression
- Genetic Markers
- Genotype
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Homozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data