Article
Polymorphism of HLA-DRB, -DQA1, and -DQB1 in rheumatoid arthritis in Asian Indians: association with DRB1*0405 and DRB1*1001.
Human immunology - 1 Mar 1996
Taneja V, Giphart M J, Verduijn W, Naipal A, Malaviya A N, Mehra N K
Abstract excerpt
We investigated the DRB, DQA1, and DQB 1 polymorphism and haplotypes in sporadic and familial RA subjects of Asian Indian origin by PCR oligotyping using biotinylated SSOPs. Molecular subtyping of DRB 1*04 in RA patients showed strongest association with highest relative risk with DRB 1*0405, followed by DRBI*0401. A significant decreased frequency of DRBI*1502 was observed in patients compared to controls (chi 2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
