Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of three polymorphisms in the translated region of PLC-gamma1 and their investigation in lithium responsive bipolar disorder.

American journal of medical genetics - 8 Apr 2001

Ftouhi-Paquin N, Alda M, Grof P, Chretien N, Rouleau G, Turecki G

Abstract excerpt

Recently, we have found an association between bipolar disorder patients who are excellent responders to lithium prophylaxis and a polymorphic marker located in the first intron of the phospholipase C-gamma1 gene (PLC-gamma1) [Turecki et al., 1998: Mol Psychiatry 3:534-538]. As this variant is not known to be functional, we searched for other markers within the coding region, using single-strand conformational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Lithium

Share to Open Reading Frames

Share to Phospholipase C gamma

Share to Polymorphism, Single-Stranded Conformational

Share to Type C Phospholipases

Source

Identifiers

PMID: 11353454
DOI: 10.1002/ajmg.1326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of three polymorphisms in the translated region of PLC-gamma1 and their investigation in lithium responsive bipolar disorder.PMID 11353454Read ↗

Evidence for a role of phospholipase C-gamma1 in the pathogenesis of bipolar disorder.Semantic proximity Read ↗

The phospholipase C-gamma1 gene (PLCG1) and lithium-responsive bipolar disorder: re-examination of an intronic dinucleotide repeat polymorphism.Semantic proximity Read ↗

Association study of the INPP1, 5HTT, BDNF, AP-2beta and GSK-3beta GENE variants and restrospectively scored response to lithium prophylaxis in bipolar disorder.Semantic proximity Read ↗

The polymorphic inositol polyphosphate 1-phosphatase gene as a candidate for pharmacogenetic prediction of lithium-responsive manic-depressive illness.Semantic proximity Read ↗

[Evaluation of the Association between Lithium Treatment and GSK3β Polymorphism in Bipolar Disorder Patients].Semantic proximity Read ↗

Association study of the glycogen synthase kinase-3beta gene polymorphism with prophylactic lithium response in bipolar patients.Semantic proximity Read ↗

Exploring Genetic Variability at PI, GSK3, HPA, and Glutamatergic Pathways in Lithium Response: Association With IMPA2, INPP1, and GSK3B Genes.Semantic proximity Read ↗

Association analysis between the human interleukin 1beta (-511) gene polymorphism and susceptibility to febrile convulsions.Semantic proximity Read ↗

Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism.Semantic proximity Read ↗

Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta -50 T/C SNP.Semantic proximity Read ↗

Glycogen synthase kinase 3β gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium.Semantic proximity Read ↗

Haplotype analysis of GSK-3β gene polymorphisms in bipolar disorder lithium responders and nonresponders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.