Article
Association analysis between the human interleukin 1beta (-511) gene polymorphism and susceptibility to febrile convulsions.
Neuroscience letters - 6 Dec 2002
Tilgen Nikola, Pfeiffer Heike, Cobilanschi Joana, Rau Birgit, Horvath Steve, Elger Christian E, Propping Peter, Heils Armin
Abstract excerpt
Recently, an association between a regulatory polymorphism in the gene encoding the pro-inflammatory cytokine interleukin (IL)-1beta and febrile convulsions (FC) has been reported. In this study we attempted to confirm these findings in a sample consisting of 99 FC patients and 126 ethnically matched controls. Since about 3% of all FC patients experience unprovoked seizures (epilepsy) later during life we...
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