Article
An Asp-CaM complex is required for centrosome-pole cohesion and centrosome inheritance in neural stem cells.
The Journal of cell biology - 7 Dec 2015
Schoborg Todd, Zajac Allison L, Fagerstrom Carey J, Guillen Rodrigo X, Rusan Nasser M
Abstract excerpt
The interaction between centrosomes and mitotic spindle poles is important for efficient spindle formation, orientation, and cell polarity. However, our understanding of the dynamics of this relationship and implications for tissue homeostasis remains poorly understood. Here we report that Drosophila melanogaster calmodulin (CaM) regulates the ability of the microcephaly-associated protein, abnormal spindle...
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