Article
Plasma levels of apolipoprotein E and cognitive function in old age.
Annals of the New York Academy of Sciences - 1 Apr 2007
Mooijaart Simon P, van Vliet Peter, van Heemst Diana, Rensen Patrick C N, Berbée Jimmy F P, Jolles Jelle, de Craen Anton J M, Westendorp Rudi G J
Abstract excerpt
The relationship between structural variants of the apolipoprotein E gene, APOE epsilon2/epsilon3/epsilon4, and dementia is well established, whereas the relationship of plasma apoE levels with dementia is less clear. Plasma apoE levels are under tight genetic control but vary widely within the various genotypes indicating that the APOE epsilon2/epsilon3/epsilon4 locus explains only a small fraction of this...
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