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Article

Angiogenesis and p53 expression in the colorectal adenoma-carcinoma sequence.

Oncology research - 1 Jan 2000

Kakolyris S A, Kaklamanis L G, Koukourakis M J, Giatromanolaki A, Rousomoustakaki M, Souglakos J C, Reppa D K, Georgoulias V A, Gatter K C, Harris A L

Abstract excerpt

Angiogenesis, the formation of new vessels, is essential for tumor growth and metastasis. Mutations of p53 tumor suppressor gene are frequent and play an important role in colorectal oncogenesis. A role of p53 as an angiogenesis inhibitor has also been proposed. We evaluated angiogenesis and p53 expression in 16 hyperplastic polyps, 35 solitary tubular and tubulovillous adenomas, and 47 cases of sporadic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11341470
DOI: 10.3727/096504001108747693

Genes

MVD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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