Article
Ovarian cancer p53 mutation is associated with tumor microvessel density.
Gynecologic oncology - 1 Jul 2002
Goodheart Michael J, Vasef Mohammad A, Sood Anil K, Davis Charles S, Buller Richard E
Abstract excerpt
OBJECTIVE: The objective of this study was to investigate the relationship between microvessel density, as measured by CD31 staining, and histopathologic factors as well as p53 tumor suppressor gene mutation in ovarian cancer. METHODS: Ovarian cancers (n = 77) were analyzed for p53 gene mutations and CD31 immunohistochemical expression. Histopathologic and mutational data were related to CD31 staining utilizing...
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