Article
Characterization of molecular abnormalities in human fibroblastic neoplasms: a model for genotype-phenotype association in soft tissue tumors.
Cancer research - 1 Apr 2001
Hoos A, Lewis J J, Antonescu C R, Dudas M E, Leon L, Woodruff J M, Brennan M F, Cordon-Cardo C
Abstract excerpt
Desmoid tumors and fibrosarcomas (FS) are part of a wide spectrum of disordered fibroblastic growth that display striking clinical and phenotypic differences. This study was designed to characterize molecular abnormalities that are associated with these differences and to determine their clinical relevance. A cohort of 24 desmoid tumors and 25 low-grade (LG) and 14 high-grade (HG) FS that were clinically and...
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