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Article

Protein kinase C-delta phosphorylates Ebp1 and prevents its proteolytic degradation, enhancing cell survival.

Journal of neurochemistry - 1 Mar 2007

Liu Zhixue, Liu Xia, Nakayama Keiichi I, Nakayama Keiko, Ye Keqiang

Abstract excerpt

ErbB3-binding protein (Ebp1) promotes cell survival by preventing apoptotic DNA fragmentation through a complex with active nuclear Akt. Ebp1 phosphorylation by protein kinase C (PKC)-delta mediates its binding to nuclear Akt. In this study, we show that Ebp1 itself acts as a substrate of active...

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Identifiers

PMID: 17316401
DOI: 10.1111/j.1471-4159.2006.04313.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17316401-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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