Article
LINE-1-derived poly(A) microsatellites undergo rapid shortening and create somatic and germline mosaicism in mice.
Molecular biology and evolution - 1 Mar 2013
Grandi Fiorella C, Rosser James M, An Wenfeng
Abstract excerpt
Interspersed and tandem repeat sequences comprise the bulk of mammalian genomes. Interspersed repeats result from successive replication by transposable elements, such as Alu and long interspersed element type 1 (L1). Microsatellites are tandem repeats of 1-6 base pairs, among which poly(A) microsatellites are the most abundant in the human genome. The rise and fall of a microsatellite has been depicted as a life...
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