Article
Allelic loss of chromosome 2p21-16.3 is associated with reduced survival in sporadic colorectal cancer.
Scandinavian journal of gastroenterology - 1 Apr 2001
Bisgaard M L, Jäger A C, Dalgaard P, Søndergaard J O, Rehfeld J F, Nielsen F C
Abstract excerpt
BACKGROUND: Since allelic loss of genes involved in the development of colorectal cancer could serve as prognostic markers, we examined the correlation between loss of markers linked to the hMSH2/hMSH6 (2p21-16.3), hMLH1 (3p21.3), APC (5q21-22), p53 (17p13.1) and DCC (18q21.3) loci and survival in a series of 64 consecutively collected colorectal cancers. METHODS: The association between allelic loss and survival...
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