Article
Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer.
Gastroenterology - 1 Oct 1999
Castells A, Ino Y, Louis D N, Ramesh V, Gusella J F, Rustgi A K
Abstract excerpt
BACKGROUND & AIMS: Chromosomal allelic losses have a varying frequency in colorectal cancer. The aim of this study was to define the target region of allelic loss on chromosome 22q in human colorectal carcinogenesis. METHODS: Fifty-seven pairs of matched normal colonic mucosa and tumor specimens from patients with colorectal cancer, as well as 15 colon cancer-derived cell lines, were genotyped using 15...
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