Article
Pro‐ and Anti‐Inflammatory Gene Expression in the Murine Small Intestine and Liver After Chronic Exposure to Alcohol
1 Apr 2001
Abstract excerpt
BACKGROUND: Endotoxin has been proposed to play a primary role in ALD, by initiating an inflammatory cascade within the liver. Although the source of these cytokines has been presumed to be circulating monocytes or tissue macrophages, ethanol-induced, nonhepatic sources of soluble mediators recently have been identified. One potential, but not clearly defined, extrahepatic source of cytokines in ALD is the...
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