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Article

Alcohol and Cytokine‐inducible Transcription Factors

1 Dec 1996

Abstract excerpt

Cytokines, such as TNF alpha, modulate the behavior of many cells by regulating the expression of a wide array of genes. When a cytokine binds to its receptor on the cell surface, the receptor becomes activated and activates signal transduction cascades. These cascades typically involve a series of phosphorylation reactions that lead to sequential activation of various kinases. The targets of these kinases...

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PMID: 8986216
DOI: 10.1111/j.1530-0277.1996.tb01710.x

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