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Article

Kupffer cell-derived interleukin 10 is responsible for impaired bacterial clearance in bile duct-ligated mice.

Hepatology (Baltimore, Md.) - 1 Aug 2004

Abe Tetsuya, Arai Toshiyuki, Ogawa Atsushi, Hiromatsu Takashi, Masuda Akio, Matsuguchi Tetsuya, Nimura Yuji, Yoshikai Yasunobu

Abstract excerpt

Extrahepatic cholestasis often evokes liver injury with hepatocyte apoptosis, aberrant cytokine production, and-most importantly-postoperative septic complications. To clarify the involvement of aberrant cytokine production and hepatocyte apoptosis in impaired resistance to bacterial infection in obstructive cholestasis, C57BL/6 mice or Fas-mutated lpr mice were inoculated intraperitoneally with 10(7)...

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PMID: 15368446
DOI: 10.1002/hep.20301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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