Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of IRAK-M in alcohol induced liver injury.

PloS one - 1 Jan 2013

Wang Yipeng, Hu Youjia, Chao Chen, Yuksel Muhammed, Colle Isabelle, Flavell Richard A, Ma Yun, Yan Huiping, Wen Li

Abstract excerpt

Increasing evidence suggests that innate immunity plays an important role in alcohol-induced liver injury and most studies have focused on positive regulation of innate immunity. The main objective of this study was to investigate the negative regulator of innate immunity, IL-1/Toll-like receptor (TLR) signaling pathways and interleukin receptor-associated kinase-M (IRAK-M) in alcoholic liver injury. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, Myelomonocytic
Share to Interleukin-1 Receptor-Associated Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestines

Share to Liver Diseases, Alcoholic

Share to Metagenome

Share to Permeability

Share to Phagocytosis

Share to Physical Chromosome Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 23437317
DOI: 10.1371/journal.pone.0057085
PMCID: PMC3578822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of IRAK-M in alcohol induced liver injury.PMID 23437317Read ↗

Role of Toll-like receptors in liver health and diseaseSemantic proximity Read ↗

Innate Immunity and AlcoholSemantic proximity Read ↗

Ambiguous Pathogenic Roles of Macrophages in Alcohol-Associated Liver DiseasesSemantic proximity Read ↗

Leukocytes, Systemic Inflammation and Immunopathology in Acute-on-Chronic Liver Failure.Semantic proximity Read ↗

Hepatitis regulation by the inflammasome signaling pathwaySemantic proximity Read ↗

Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver diseaseSemantic proximity Read ↗

Macrophage Phenotype and Function in Liver Disorder.Semantic proximity Read ↗

Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice.Semantic proximity Read ↗

Macrophages and Alcohol-Related Liver Inflammation.Semantic proximity Read ↗

Restricted immunological and cellular pathways are shared by murine models of chronic alcohol consumptionSemantic proximity Read ↗

TLR4 signaling and the inhibition of liver hepcidin expression by alcohol.Semantic proximity Read ↗

Unraveling the Complex Interplay between Epigenetics and Immunity in Alcohol-Associated Liver Disease: A Comprehensive ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.