Article
Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays
27 Apr 2001
Abstract excerpt
Oligonucleotide DNA microarrays were investigated for utility in measuring global expression profiles of drug metabolism genes. This study was performed to investigate the feasibility of using microarray technology to minimize the long, expensive process of testing drug candidates for safety in animals. In an evaluation of hybridization specificity, microarray technology from Affymetrix distinguished genes up to...
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