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Article

Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories.

BMC genomics - 12 Jun 2008

Boedigheimer Michael J, Wolfinger Russell D, Bass Michael B, Bushel Pierre R, Chou Jeff W, Cooper Matthew, Corton J Christopher, Fostel Jennifer, Hester Susan, Lee Janice S, Liu Fenglong, Liu Jie, Qian Hui-Rong, Quackenbush John, Pettit Syril, Thompson Karol L

Abstract excerpt

BACKGROUND: The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals within the control arm of toxicogenomics studies could yield useful information on baseline fluctuations in gene expression, although...

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Identifiers

PMID: 18549499
DOI: 10.1186/1471-2164-9-285
PMCID: PMC2453529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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